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HEXAFLUORO-DL-VALINE

  • Name HEXAFLUORO-DL-VALINE
  • CAS 16063-80-2
  • Purity 99%
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1.What is the HEXAFLUORO-DL-VALINE ?

Hexafluoro-DL-valine is a synthetic amino acid derivative that closely resembles native amino acids such as valine. It is characterized by its high degree of fluorination, which makes it valuable in medicinal chemistry and pharmaceutical research. HEXAFLUORO-DL-VALINE is known for its unique physiochemical properties, such as increased lipophilicity and metabolic stability, as well as its potential for interaction with biological targets. Its presence of fluorine also impacts its Nuclear Magnetic Resonance (NMR) properties, making it significant in the study of protein-ligand interactions and bio-molecular structures.

Used in Medicinal Chemistry:
Hexafluoro-DL-valine is used as a building block for the synthesis of complex bioactive compounds, particularly potent enzyme inhibitors. Its high degree of fluorination contributes to its utility in this application.
Used in Pharmaceutical Research:
In pharmaceutical research, hexafluoro-DL-valine is employed for its unique physiochemical properties, which include increased lipophilicity and metabolic stability. These properties make it a valuable compound in the development of new drugs.
Used in Protein-Ligand Interaction Studies:
Hexafluoro-DL-valine is used as a tool in the study of protein-ligand interactions due to the impact of its fluorine content on NMR properties. This allows researchers to gain insights into the binding mechanisms and structural aspects of these interactions.
Used in Bio-molecular Structure Analysis:
HEXAFLUORO-DL-VALINE is also utilized in the analysis of bio-molecular structures, where its NMR properties are leveraged to understand the conformational changes and dynamics of proteins and other biomolecules.

2.What is the CAS number for HEXAFLUORO-DL-VALINE ?

The CAS number of HEXAFLUORO-DL-VALINE is 16063-80-2.

More information of HEXAFLUORO-DL-VALINE 16063-80-2 are:

CAS?Number

16063-80-2

Density

1.575 g/cm3

Melting Point

204 °C (dec.)

Boiling Point

165.9 °C at 760 mmHg

Flash Point

54.1 °C

Refractive Index

1.349

HS CODE

2922499990

PSA

63.32000

LogP

1.83940

Pka

1.53±0.10(Predicted)

3.What is the molecular formula of HEXAFLUORO-DL-VALINE ?

The chemical formula of?HEXAFLUORO-DL-VALINE is C5H5F6NO2 which containing 5 Carbon atoms,5 Hydrogen atoms,6 Fluorine atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of HEXAFLUORO-DL-VALINE is 225.091

4.What is HEXAFLUORO-DL-VALINE(16063-80-2)used for?

Hexafluoro-DL-valine is a synthetic amino acid derivative that closely resembles native amino acids such as valine. It is characterized by its high degree of fluorination, which makes it valuable in medicinal chemistry and pharmaceutical research. HEXAFLUORO-DL-VALINE is known for its unique physiochemical properties, such as increased lipophilicity and metabolic stability, as well as its potential for interaction with biological targets. Its presence of fluorine also impacts its Nuclear Magnetic Resonance (NMR) properties, making it significant in the study of protein-ligand interactions and bio-molecular structures.

InChI:InChI=1/C5H5F6NO2/c1-4(8,2(6)7)5(9,3(13)14)12(10)11/h2H,1H3,(H,13,14)/t4?,5-/m1/s1

Relevant articles related to HEXAFLUORO-DL-VALINE:

Article

Source

Synthesis of [Hexafluorovalyl1,1′]gramicidin S

Arai, Toru,Imachi, Takashi,Kato, Tamaki,Ogawa, H. Iyehara,Fujimoto, Tsutomu,Nishino, Norikazu

, p. 1383 - 1389 (2007/10/03)

5.Good factory supply good HEXAFLUORO-DL-VALINE 16063-80-2

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